Sebastien Benzekry is a scientific research director (DR, PhD, HDR) at Inria, the French institute for applied mathematics, computer science and their applications. He has created in 2021 and since then leads the joint Inria (French national institute for digital science) – Inserm (French national institute for biomedical research) project-team COMPO (COMPutational pharmacology and clinical Oncology), located at the Center for Research on Cancer of Marseille (Pharmacy faculty, Aix-Marseille University). The objective of his research is to model data arising from (clinical) oncology in order to 1) bring clinical decision tools to enhance therapeutic management, 2) better inform and design clinical trials and 3) test biological hypotheses. To do so, he combines mechanistic models (i.e., simulation models of the pharmaco-patho-physiological processes, also called "digital twins"), and statistical learning through an approach termed 'mechanistic learning'. He has fifteen years of experience in trans-disciplinary projects in oncology. His main topics of research are modeling metastatic development and immuno-oncology, integrating longitudinal data. These are implemented into several open source software.
Dr Benzekry has an initial training in applied mathematics (Ecole Normale Supérieure) followed by a PhD at Aix-Marseille University and a postdoc in the Center for Cancer and Systems Biology, Tufts Univ, Boston, MA.
https://team.inria.fr/compo/
https://www-sop.inria.fr/members/Sebastien.Benzekry/index.html
https://scholar.google.fr/citations?user=xsLpdFAAAAAJ&hl=fr&oi=ao