Lynnette Fernandez-Cuesta has more than 15 years of experience in the field of thoracic cancer functional genomics. During her postdoc in the Max Planck Institute and Department of Translational Genomics in Cologne, Germany, she led the characterization of the genomic landscape of lung neuroendocrine neoplasms, identifying major molecular drivers of small-cell lung cancer, large-cell neuroendocrine carcinoma, and pulmonary carcinoids. She also led the discovery of recurrent NRG1 fusions in lung adenocarcinomas from never-smokers. As a principal investigator at IARC-WHO, she launched the Rare Cancers Genomics initiative, leading to major breakthroughs in the field of thoracic tumors with the lungNENomics and MESOMICS projects. One to highlight is the discovery of supra-carcinoids. She currently leads, together with Matthieu Foll, the Computational Cancer Genomics team at IARC-WHO.