During his scientific career, Eric Tartour made several pioneer scientific observations in the tumor-immunology field : i) In collaboration with Ludger Johannes, he provide the proof of concept in preclinical model of the value to target antigen to dendritic cells to enhance specific CD8+T cells (Lee RS Eur J Immunol 1998)(Haicheur N J Immunol 2000) ii) he demonstrated the pro-and anti-tumor immunity of the cytokine interleukin-17 (Tartour E Cancer Res 1999)(Benchetrit F Blood 2002). This ambivalent activity of this cytokine has been generalized to most other cytokines. iii) He firstly showed that TH1 cytokine in the tumor microenvironment may be associated with a good prognosis (Tartour E et al J Natl Cancer Inst 1998). iv) He also recently provided arguments about the need to induce local mucosal tumor immunity to control mucosal tumors (Sandoval F Sci Transl Med 2013)(Nizard Clin Cancer Res 2016).
Eric Tartour
- Wordpackage: WP3 : Mapping and targeting tumor immune and non-immune environment
- Institution: CRC - Hôpital Georges Pompidou, Paris
- Current position:
- PU-PH. Directeur Equipe INSERM et Chef du service d’immunologie Hôpital Européen Georges Pompidou